Acetylation相关论文
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mi
Parkin,an E3 ubiquitin ligase,plays a role in maintaining mitochondrial homeostasis through targeting damaged mitochondr......
LATS1 K751 acetylation blocks activation of Hippo signalling and switches LATS1 from a tumor suppres
Large tumor suppressor 1 (LATS1) is the key kinase controlling activation of Hippo signalling pathway.Post-translational......
SL010110,a lead compound,inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and imp
Suppression of excessive hepatic gluconeogenesis is an effective strategy for controlling hyperglycemia in type 2 diabet......
Hypertrophic preconditioning attenuates myocardial ischemia/reperfusion injury through the deacetyla
To test the hypothesis that transient nonischemic stimulation of hypertrophy would render the heart resistant to subsequ......
Icariin Improves Cognitive Impairment after Traumatic Brain Injury by Enhancing Hippocampal Acetylat
Objective: To examine the effect of icariin (ICA) on the cognitive impairment induced by traumatic brain injury (TBI) in......
Mass spectrometry analysis of the variants of histone H3 and H4 of soybean and their post-translatio
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Thermo-Mechanical Properties of the Composite Made of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) a
The polar hydroxyl groups on the polysaccharide nanocrystals inhibit the positive function of the polysaccharide nanocry......
High Glucose-induced TRIB3 Promotes CRC Tumorigenesis and Progression via Upregulating Wnt/betacaten
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Insulin-Like Growth Factor 1 Induced Enolase 2 Deacetylation by Histone Deacetylase 3 Promotes Metas
Objective Background and Aims: Although the dysregulation of lysine acetylation(Kac)in the majority of intermediate meta......
Objective Non-histone protein acetylation in cancer cell regulates diverse biological functions that have been associate......
Genes that exhibit differential expression behaviors are called pattern genes (Pan et al.,2012).Four kinds of pattern ge......
Ribonucleotide reductase(RNR),composed of RRM1 and RRM2 subunits,catalyzes the rate-limiting step in the de novo synthes......
HBO1,a member of the MYST family histone acetyltransferases(HATs),is required for global acetylation of H3K14 and embryo......
The abundant expression of IFNγ in ThPOK-deficient CD4+ T cells requires the activation of Eomesodermin (Eomes);however......
Osterix (Osx) , a C2H2-type zinc-finger containing transcription factor, plays an essential role in controlling osteobla......
Acetylation of Bovine Foamy Virus Transactivator BTas by p300 Augments Promoter-binding Affinity and
Recent reports showed that several histone acetyltransferases (HATs) could acetylate transactivators of retrovirus and s......
Reducing the cytotoxicity while improving the anti-cancer drug loading capacity of polypropylenimine
Polypropylenimine (PPI) dendrimers have been widely used as effective deliveryvehicles for drugs and nucleic acids durin......
PhoP is an essential transcription factor for virulence in Salmonella.Our previous study showed that the acetylation of ......
As a genome guardian,p53 maintains genome stability by arresting cells for damage repair or inducing cell apoptosis to e......
Reducing the cytotoxicity while improving the anti-cancer drug loading capacity of polypropylenimine
Polypropylenimine (PPI) dendrimers have been widely used (i)s effective delivery vehicles for drugs and nucleic acids du......
Interferon regulatory factor-1 mediates the release of high mobility group box-1 in endotoxemia in m
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Ubiquitin-specific protease 31 (USP31) is a member of deubiquitinase family that is involved in nuclear factor-κB activ......
A domesticated Harbinger transposase forms a complex with HDA6 and promotes histone H3 deacetylation
In eukaryotes,histone acetylation is a major modification on histone N-terminal tails that is tightly connected to trans......
Barley NLR Receptor Triggers Immunity by Derepressing Defense Transcriptions through Acetylation and
Plant employs NLR receptors to recognize isolate-specific effectors and induce massive transcriptional reprogramming......
The tumor suppressor protein p53 is a well-known transcription factor that functions as a critical component of the geno......
A biomarker is a measurable indicator associated with changes in physiological state or disease.In contrast to the blood......
SYNTHESIS AND STRUCTURE OF α’-ACE-TYL-α-THIENYL PHENYLACETYLENEDI-COBALT HEXACARBONYL AND α’-ACE-TYL
Friedel-Crafts acylation of α-thienyl phenylacetylenedicobalt hexacarbonyl with acetyl chlo-ride has been investigated.......
目的探索高氟暴露是否会影响外周血组蛋白乙酰化水平，氟骨症患者的组蛋白乙酰化水平是否存在异常，尝试从转录修饰水平上研究氟骨症的......
目的 探讨低剂量无机砷对人正常肝细胞(L-02)中Sirt1及细胞周期相关基因表达的影响.方法 0.0(对照)、0.1、0.2、0.4 μmol/L三氧化......
Slug,a member of the Snail family of transcriptional repressors,plays a key role in cancer progression,cellular plastici......
目的:探讨KLF7b对斑马鱼胚胎发育的影响.方法:体外转录野生型KLF7b m RNA、KLF7b乙酰化位点突变体m RNA;设计合成特异性KLF7b反义......
目的通过对急性冠脉综合征(acute coronary syndrome，ACS)患者外周血CD4＋T细胞CD28 mRNA水平和CD28基因启动子区域组蛋白H4(histone ......
Periploca sepium, Salix psammophila and Tamarix spp. make up an important part of the local vegetation in the sandland o......
目的 探索脊髓p300在大鼠慢性缩窄性神经损伤(CCI)模型所致神经病理性疼痛中的作用.方法 32只雄性SD大鼠随机分为假手术组(Sham组)......
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以二氢杨梅素(6)为原料,在不同的催化条件下与不同的酰化试剂进行乙酰化反应制备得3,5,7,3’,4’,5’-六乙酰基二氢杨梅素(1)、3,3......
[目的]建立同时测定尿液中2-氯酚、2,4-二氯酚、2,4,6-三氯酚及五氯酚4种氯酚的气相色谱串联质谱(GC-MS/MS)方法。[方法]尿样经盐......
Protein stability regulators screening assay (Pro-SRSA):protein degradation meets the CRISPR-Cas9 li
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
V(HSO4)3 catalyzed chemoselectivity acetylation of alcohols and phenols in solution and under solven
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
p-Toluenesulfonyl chloride as a new and effective catalyst for acetylation and formylation of hydrox
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
A mild and efficient method for the methoxymethylation and acetylation of alcohols promoted by benzy
A mild and efficient method for the conversion of alcohols to their corresponding methoxymethyl ethers and acetates usin......
Pharmacokinetics and acetylation of sulfamethoxazole in turbot Scophthalmus maximus after intravascu
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
N-Sulfonic acid poly(4-vinylpyridinum) hydrogen sulfate as a novel, efficient, and reusable solid ac
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
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为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
近年来研究表明表观遗传学异常是白血病发病机制中的重要组成部分.许多白血病都伴随表观遗传学的异常变化.白血病的DNA去甲基化治......
KLF4为锌指蛋白转录因子,含特异性转录激活区和转录抑制区,体内分布广泛,在不同的肿瘤组织中,通过抑制细胞增殖、调节细胞分化、细......
